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Man City who has won their last four Champions League matches carry a slight advantage into this fixture having won the first leg 2-1 at home.
Pep Guardiola handed seven of his key players a rest last weekend in readiness for this match which also presents them with an opportunity to redeem themselves from a shocking 2-1 loss to the league returnees.Marco Reus of Borussia Dortmund scores their team's first goal during the UEFA Champions League Quarter Final match between Manchester City and Borussia Dortmund at Etihad Stadium on April 06, 2021File
The Citizens are yet to taste defeat in this season's tournament and had kept seven clean sheets in a row until Marco Reus broke the run in the first leg.
On the other hand, Dortmund has been knocked out in six of the seven occasions when they suffered defeats in the first leg.
Kick-off 10 pm (EAT)
Sparta Prague hasn’t lost to Baumit Jablonec in the last seven meetings and is undefeated in the previous six away matches. Jablonec has not won their last two home matches.
Kick-off 6 pm (EAT)Players of Jablonec are seen posing for a photo after the UEFA Europa League Group K soccer match between FC Dynamo Kiev and FK JablonecFile
St Galen has a history of pulling surprises in the cup. The last time they crossed swords with Grasshoppers, they won 1-0 and statistics show that they have won five out of the last seven meetings.
Grasshoppers lost 4-1 to Xamax at home.
Kick-off 7 pm (EAT)