He is the current governor of Kisumu County, serving his first term after being elected into office via an ODM ticket in 2017.
The former MP of Kisumu Rural constituency has a Degree in Political Science from Uganda’s Makerere University and has a Master's and PhD in Political Science from the University of Chicago.
Nyong’o is one of the biggest beneficiaries of the handshake initiative by President Uhuru Kenyatta and ODM leader Raila Odinga, which led to the revamp of the Kisumu Port, railways upgrade and health care initiatives in the county.
In October 2020, Kisumu was ranked fourth among the most devolved counties and fourth in terms of delivery of services, in a study by Infortrak Research and Consulting for 2019-2020.
He is also a champion for health services in the country and has severally called for the construction of several cancer ontologies. Nyong’o is a cancer warrior.
The former Kisumu Senator supports the Building Bridges Initiative (BBI) and has made several rallying calls supporting the referendum as the best module to amend the constitution.